Pathogenesis of Long COVID

Considerations for etiology and treatment that can help fill underlying knowledge gaps

Post-acute Sequelae of SARS-CoV-2 Infection (PASC) is not only a mouthful but also the formal name for a set of effects now experienced by millions of people. Fortunately, the NIH and others are giving the conditions increased attention. But it’s critically important to use those resources in the most promising ways. Kudos to the researchers pursuing inflammation’s role in Post-COVID conditions, but there are other mechanisms to explore, especially those involving mitochondria and microglia.